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軸抑制蛋白2重組兔單抗

簡要描述:Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B.
Involvement in disease:Defects in AXIN2 are involved in colorectal cancer (CRC). They appear to be specifically associated with defective mismatch repair.
Defects in AXIN2 are the cause of oligodontia-colorectal cancer syndrome (ODCRCS). Affected individuals manifest severe tooth agenesis and colorectal cancer or precancerous lesions of variable type

  • 產(chǎn)品型號:bsm-61459R
  • 廠商性質(zhì):生產(chǎn)廠家
  • 更新時間:2025-03-01
  • 訪  問  量: 55

詳細(xì)介紹

Human,Mouse,Rat
WB,IHC-P,IHC-F,ICC/IF,IF
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

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